Invasive Ductal Carcinoma of the Breast with Metastasis to the Uterine Cervix

Jalal Qawasmeh, Maysa A-Hussaini and Sami Koro

Department of Radiation Oncology, King Hussein Cancer Center, Jordan Department of Pathology, King Hussein Cancer Center, Jordan

^*Correspondance to: Jalal Qawasmeh 

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Abstract:

Hematogenous metastasis of breast cancer tumors frequently occur at the lung, bones, liver and brain. However, presence in the cervix remains rare, since the majorities of tumors in this organ are primary carcinomas or result from the direct extension of primary pelvic tumors. The number of reported metastases to the uterus and cervix remains low. Invasive lobular carcinoma spreads to gynecologic organs more frequently than invasive ductal carcinoma. We report a rare clinical case, as well as discuss its implications and peculiarities. A 64-year-old postmenopausal woman with invasive ductal carcinoma metastatic to the cervix more than 15 years after the termination of bilateral breast cancer treatment. A literature analysis confirmed that most cases presented with vaginal bleeding or abdominal discomfort, but many were asymptomatic. Common characteristics between the cases were the patient’s age, the time period between primary tumor diagnosis and the emergence of metastatic lesions, treatment, medication, and signs/symptoms. Although rare, metastasis should be considered in women with a history of breast cancer, particularly with abnormal vaginal bleeding as a symptom.

Keywords:

Breast cancer; Cervix; Metastasis; Histopathology; Immunohistochemistry

Cite the Article:

Qawasmeh J, A-Hussaini M, Koro S. Invasive Ductal Carcinoma of the Breast with Metastasis to the Uterine Cervix. Clin Case Rep Int. 2020; 4: 1172.