Journal Basic Info
- Impact Factor: 0.285**
- H-Index: 6
- ISSN: 2638-4558
- DOI: 10.25107/2638-4558
Major Scope
- Diabetology
- Sleep Medicine and Disorders
- Sleep Disorders & Sleep Studies
- Medical Radiography
- Hepatology
- Internal Medicine
- Allergy & Immunology
- Sexual Health
Abstract
Citation: Clin Case Rep Int. 2021;5(1):1207.DOI: 10.25107/2638-4558.1207
Fatal Metformin Poisoning with Associated Lactic Acidosis
Mansur A Ramalan, Andrew Uloko, Ibrahim Gezawa and Amin Zaitun
Endocrinology, Diabetes and Metabolic Unit, Aminu Kano Teaching Hospital, Kano, Nigeria Pulmonology Unit, Aminu Kano Teaching Hospital Unit, Kano, Nigeria
*Correspondance to: Mansur A Ramalan
PDF Full Text Case Report | Open Access
Abstract:
Metformin is one of the most widely used anti-diabetic medication. Lactic acidosis although very rare is a serious complication of metformin use. It can be life-threatening with mortality as high as 50% if not recognized and treated early. We report a rare case of fatal metformin poisoning due to severe lactic acidosis following a 40 yr old divorcee with primary infertility secondary to polycystic ovarian syndrome. Treatment of metformin induced lactic acidosis involves the use of renal replacement therapy, sodium bicarbonate infusion and general measures. This case was reported in order to alert physicians on the existence of this rare but life-threatening endocrine emergency. Late presentation was a major limiting factor in the management of this patient.
Keywords:
Lactic acidosis; Metformin; Coma; Suicide
Cite the Article:
Ramalan MA, Uloko A, Gezawa I, Zaitun A. Fatal Metformin Poisoning with Associated Lactic Acidosis. Clin Case Rep Int. 2021; 5: 1207. .