Improved Post-Stillbirth Depression and Medical Adherence during Embryo Preservation Resulting in a Livebirth in a Woman with Chronic Hypertension and Systemic Lupus Erythematosus: A Case Report

Nishimura T, Tanaka Y, Kiyokawa H, Fukuhara K, Yoshida T, Saegusa J and Honda T

Department of Obstetrics and Gynecology, Kurashiki Central Hospital, Japan
Department of Endocrinology and Rheumatology, Kurashiki Central Hospital, Japan
Department of Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Japan

^*Correspondance to: Tomoki Nishimura 

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Abstract:

Blood Pressure (BP) control, before conception or since early pregnancy, is important in pregnancy with Chronic Hypertension (CH). We present a woman with CH and Systemic Lupus Erythematosus (SLE), whose Fertility Preservation (FP) in pregnancy-prohibited phase may have contributed to BP control and a livebirth. A 33-year-old woman with CH and SLE conceived twins in SLE remission, without BP control. Both SLE flare and superimposed preeclampsia occurred, and the pregnancy was terminated because of renal dysfunction at 20 weeks. She presented with depression and decreased medical adherence, resulting in prolonged hypertension and pregnancy prohibition. FP was started 40 weeks after stillbirth, and a blastocyst was preserved at the fifth oocyte retrieval. Her medical adherence improved, and her BP became 120-130/90-100 mmHg. After thawed embryo transfer, she conceived a singleton pregnancy. Her BP was 120-130/70-90 mmHg during this pregnancy. At 32 weeks, she delivered a baby due to abnormal findings in Cardiotocogram. In this case, FP may have contributed to BP control and a livebirth. To our knowledge, this is the first report of FP in a pregnancy-prohibited woman with CH or SLE.

Keywords:

Autoimmune disease; Fertility preservation; Hypertension; Pregnancy; Systemic lupus erythematosus

Cite the Article:

Nishimura T, Tanaka Y, Kiyokawa H, Fukuhara K, Yoshida T, Saegusa J, et al. Improved Post-Stillbirth Depression and Medical Adherence during Embryo Preservation Resulting in a Livebirth in a Woman with Chronic Hypertension and Systemic Lupus Erythematosus: A Case Report. Clin Case Rep Int. 2023; 7: 1471..