Cushing Syndrome and Adrenal Insufficiency Following Topical Steroids Misuse: Case Report

Daly W, Aouinti I, Zaiem A, Marzouk A, Kaabi W, Charfi O, Kastalli S, Daghfous R, Ghozlane L and El Aidli S

Data Analysis and Collection Service, Centre National Chalbi Belkahia de Pharmacovigilance, Tunisia
University of Tunis El Manar, Research Unit: UR17ES12, Tunisia
Department of Pediatrics, Ben Arous Regional Hospital, Tunisia

^*Correspondance to: Wiem Daly 

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Abstract:

Introduction: Cushing Syndrome (CS) results from abnormally high blood levels of cortisol or other glucocorticoids. Prolonged exogenous administration of glucocorticoid is the most common cause of CS. In children, iatrogenic CS due to topical steroid application is rare, and only a few cases were reported in the literature. Case Report: We report the case of an infant who developed CS and adrenal insufficiency due to a topical corticosteroid, misused by her mother to treat diaper dermatitis for about a month. Conclusion: While topical steroids are prescribed to treat various skin diseases, these medications are not without risks especially when they are misused by patients or parents. Physicians need to be aware of this misuse and inform patients of the correct use of steroids.

Keywords:

Cushing syndrome; Adrenal insufficiency; Topical steroids; Adverse drug reaction; Misuse

Cite the Article:

Daly W, Aouinti I, Zaiem A, Marzouk A, Kaabi W, Charfi O, et al. Cushing Syndrome and Adrenal Insufficiency Following Topical Steroids Misuse: Case Report. Clin Case Rep Int. 2023; 7: 1544.